Mechanisms of outer membrane vesicle entry into host cells
نویسندگان
چکیده
منابع مشابه
Mechanisms of outer membrane vesicle entry into host cells
Bacterial outer membrane vesicles (OMVs) are nano-sized compartments consisting of a lipid bilayer that encapsulates periplasm-derived, luminal content. OMVs, which pinch off of Gram-negative bacteria, are now recognized as a generalized secretion pathway which provides a means to transfer cargo to other bacterial cells as well as eukaryotic cells. Compared with other secretion systems, OMVs ca...
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Outer membrane vesicles are nano-sized microvesicles shed from the outer membrane of Gram-negative bacteria and play important roles in immune priming and disease pathogenesis. However, our current mechanistic understanding of vesicle-host cell interactions is limited by a lack of methods to study the rapid kinetics of vesicle entry and cargo delivery to host cells. Here, we describe a highly s...
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Many respiratory diseases are caused by extracellular bacterial pathogens; however, two very important lung infections are due to intracellular pathogens, Legionnaires' disease and tuberculosis. Legionnaires' disease remains problematic due to our inability to predict where sporadic epidemics will occur and the speed at which the bacterium debilitates its victims. The development of better meth...
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ژورنال
عنوان ژورنال: Cellular Microbiology
سال: 2016
ISSN: 1462-5814
DOI: 10.1111/cmi.12655